Ozone Therapy has been utilized and extensively studied for many decades altogether. Its effects are proven, consistent and with minimal side effects. Medical O3, used to disinfect and treat disease, has been around for over 150 years. Used to treat infections, wounds and multiple diseases, O3’s effectiveness has been well-documented. It has been used to disinfect drinking water before the turn of the last century. Ozone was known to treat as many as 114 diseases.
Ozone therapy disrupts the integrity of the bacterial cell envelope through oxidation of the phospholipids and lipoproteins. In fungi, O3 inhibits cell growth at certain stages. With viruses, the O3 damages the viral capsid and upsets the reproductive cycle by disrupting the virus-to-cell contact with peroxidation. The weak enzyme coatings on cells which make them vulnerable to invasion by viruses make them susceptible to oxidation and elimination from the body, which then replaces them with healthy cells.
Ozone therapy causes an increase in the red blood cell glycolysis rate. This leads to the stimulation of 2,3-diphosphoglycerate which leads to an increase in the amount of oxygen released to the tissues. Ozone activates the Krebs cycle by enhancing oxidative carboxylation of pyruvate, stimulating production of ATP. It also causes a significant reduction in NADH and helps to oxidize cytochrome C. There is a stimulation of production of enzymes which act as free radical scavengers and cell-wall protectors: glutathione peroxidase, catalase and superoxide dismutase. Production of prostacyline, a vasodilator, is also induced by O3.
Ozone administered at a concentration of between 30 and 55 μg/cc causes the greatest increase in the production of interferon and the greatest output of tumor necrosis factor and interleukin-2. The production of interleukin-2 launches an entire cascade of subsequent immunological reactions.
Mechanism of action of O3 on the human lung: Ozone exposure induces a significant mean decrement in vital capacity. It significantly increases mean airway resistance and specific airway resistance but does not change dynamic or static pulmonary compliance or viscous or elastic work. It also significantly reduces maximal transpulmonary pressure. And further more significantly increases respiratory rate and decreased tidal volume.
Effect On Diabetes: Diabetic complications are attributed to the oxidative stress in the body, O3 was found to activate the antioxidant system affecting the level of glycemia. Ozone prevented oxidative stress by normalizing the organic peroxide levels by activating superoxide dismutase.
Diseases that can be treated with Ozone Therapy:
1. Infected wounds:
Open leg ulcers, bed sores and burns are successfully treated by Ozone in practically all cases. Clinical studies have shown that even very severe cases improve with Ozone.
2. Circulatory Disorders:
Ozone Therapy gives very good results in arterial circulatory disorders characterized by sensation of heaviness and coldness and/or pains in the legs, especially while walking. (Well known as smoker’s leg or intermittent claudications) Ozone Therapy has avoided amputation in large number of cases.
3. Geriatric conditions:
Ozone shows general revitalizing capacity (including nerve and brain functions). Therefore, it can be successfully used for poor concentration, forgetfulness, general reduction in mental and physical performance, insecurity in walking (balancing problems) and clinical dizziness or vertigo. Elderly people generally experience a feeling of well being and improved quality of life!
4. Macular degeneration:
Ozone is used improve weak eye sight due to age related retinal detachment.
5. Intestinal conditions:
Inflammatory condition of the large intestines (eg colitis) and small intestines, fistulas and proctitis (inflammation of the rectum) – many such unpleasant and inconvenient conditions are favorably treated by Rectal Insufflation of Ozone.
6. Viral Diseases:
A series of clinical trials has shown good results of Ozone treatment in painful, viral conditions like herpes and hepatitis. Ozone Therapy reduces the duration of the diseases heals more efficiently and patient is back to his normal state of well-being in short time.
7. Rheumatism/Arthritis:
Ozone Therapy, in these conditions, causes pain and inflammation to subside. Repeated treatment may even produce permanent restoration.
8. Cancer:
Ozone Therapy is give as a complementary therapy in addition to standard methods. It produces its effects by immune activation.